TWO-DIMENSIONAL MANIPULATION OF MICROBUBBLES USING STANDING LEAKY SURFACE ACOUSTIC WAVE
In this paper, a microfluidic device is developed to transport the microbubbles on a two-dimensional plane. The microfluidic device consists of a polydimethylsiloxane (PDMS) microchannel and two pairs of perpendicular interdigital transducers (IDTs). When the surface acoustic wave (SAW) contacts the fluid medium inside the microchannel, some of SAW energy is coupled to the fluid and the SAW becomes the leaky surface wave (LSAW). The superposition of two series of planar LSAW with orthogonal wave vectors generates a two-dimensional standing LSAW and a planar pressure nodes with a periodic distribution. By modulating the relative phase between the IDTs, the pressure node plane changes linearly resulting in the transportation of the microbubbles continuously. Furthermore, the radiation force on the microbubbles can be acquired since the radiation force is balanced the drag force. These results demonstrate that the device may prove useful for many biochemical studies and applications.
Microbubbles Acoustic manipulation Surface acoustic wave device Biomicrofluidics
Long Meng Fei-Yan Cai Hai-Rong Zheng
Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
国际会议
深圳
英文
317-320
2011-12-09（万方平台首次上网日期，不代表论文的发表时间）