Nipah Virus Classification via Fractal Dimension & Shannon Entropy

摘要：

Nipah virus glycoprotein and nucleoprotein sequences were studied using fractal dimension and Shannon entropy. The nucleotide atomic number fluctuation forms the basis of the phylogeny study. The classification reproduces the main results of traditional phylogeny analysis, but with better ability to distinguish closely related strains. The fractal dimension correlation with the GC pair content in the glycoprotein sequence and di-nucleotide entropy in the nucleoprotein suggests different evolutionary mechanisms or strategies. Extension to other flu virus suggests that low fractal dimensionality in the nucleoprotein sequence could be a marker for the Nipah and Spanish-flu-like viruses.

作者: Todd Holden N.Gadura E.Cheung P.Schneider G.Tremberger N.Elham D.Sunil D.Lieberman T.Cheung

作者单位: Physics and Departments CUNY Queensborogh Community College Bayside, NY 11364 USA Biology Departments CUNY Queensborogh Community College Bayside, NY 11364 USA

会议类型: 国际会议

会议名称: The 4th International Conference on Bioinformatics and Biomedical Engineering(第四届IEEE生物信息与生物医学工程国际会议 iCBBE 2010)

会议地点: 成都

会议语种:英文

页码: 1-4

在线出版日期: 2010-06-18（万方平台首次上网日期，不代表论文的发表时间）