Characterization of Electrically Evoked Compound Action Potential Amplitude Growth Function in Cochlear Implant users
A multichannel cochlear implant (CI) is designed totake advantage of the tonotopic arrangement of auditory nervefibers within a cochlea. The electrically evoked compound actionpotential (ECAP) is a safe and reliable objective measure forqualifying neural survival and local spatial resolution in thecochlea. The present study was aimed to explore the effect ofrecording position on the ECAP Amplitude Growth Function(AGF). The stimulating electrode (EL) was fixed at EL8, in themiddle of the electrode array in 6 Clarion II or HiRes 90Ksubjects. The ECAP AGFs were obtained respectively from tworecording positions (EL6 and EL10) using monopolar stimulationmode. The result showed that, in all subjects for both EL6 andEL10 recording positions, the ECAP is a linear function ofstimuli level (Mean R 2=0.96, standard deviation=0.06).Moreover, there was a significant correlation of the ECAP AGFsrecorded from EL6 and EL10. These results demonstrate thefundamentals of the electrical hearing and will be utilized in theclinical application for diagnosing neural degeneration of CIusers
Ziyan Zhu Qing Tang Fan-Gang Zeng Tian Guan Datian Ye
Department of Biomedical Engineering, Tsinghua University, Beijing, China Research Center of Biomedi Department of Biomedical Engineering, University of California, Irvine, CA, USA Research Center of Biomedical Engineering, Graduate School at Shenzhen, Tsinghua University, Shenzhe
国际会议
成都
英文
1-4
2010-06-18（万方平台首次上网日期，不代表论文的发表时间）