The Application of Apriori-Gen Algorithm in the Association Study in Type 2 Diabetes

摘要：

Study shows type 2 diabetes is a genetic disease and evidence of a statistical interaction among several SNPs has been reported.Gene-gene interaction analysis has been used to identify common disease susceptibility genes.This paper explores the application of Apriori-Gen algorithm on the association study among SNPs.The algorithm has been applied to SNP data of type 2 diabetes for association study.The result shows the interaction among 5 SNPs with support s of 50％ and confidence α of 60％.The risk rate RR and odds ratio OR are 2.14 and 2.92, respectively.The experiment results indicate that the interaction among those SNPs is associated with the disease.

作者: Weidong Mao Jinghe Mao

作者单位: Department of Mathematics & Computer Science Virginia State University Petersburg,VA 23806,USA Department of Biology Tougaloo College Tougaloo,MS 39174,USA

会议类型: 国际会议

会议名称: The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 1-4

在线出版日期: 2009-06-11（万方平台首次上网日期，不代表论文的发表时间）