A novel model for individual dosing regimens against PK-PD correlation

摘要：

Recently, computers are increasingly being used in drug design, patient management, disease diagnosis, and estimating prognosis. While it showed tremendous advantages, many drugs cannot exert their maximal efficacy in the process of treatment, even generate severe side-effect. This may be attributed to the differences between the pharmacokinetic(PK) -pharmacodynamic(PD) properties of the drug in the different groups of people who have different characteristics included age, gender, genetic, height, nation, status etc. It is very valuable to balance the PK-PD relationship to put forward the model for individual dosing regimens. It can predict the dosing regimens of different people. The idea may bring the revolution of medical care.

关键词： computers efficacy pharmacokinetic(PK)-pharmacodyn amic(PD) individual dosing regimens

作者: Yingzhu Feng Bochu Wang Shuangkou Chen Pengyu Shao

作者单位: College of Bioengineering Chongqing University Chongqing,China

会议类型: 国际会议

会议名称: The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 1-3

在线出版日期: 2009-06-11（万方平台首次上网日期，不代表论文的发表时间）