The characteristics of ultrasound speed and attenuation in progressive trypsin digested articular cartilage
Articular cartilage is a biological weight-bearing tissue covering the bony ends of articulating joints.Subtle changes in tissue composition can lead to degeneration of articular cartilage.Some studies indicated that ultrasound acoustic parameters are related with the degeneration of articular cartilage.The aim of this study is to investigate the changes of ultrasound speed and attenuation in progressive trypsin digested articular cartilage using high frequency ultrasound.Fresh intact cartilage specimens were monitored with a 25MHz ultrasound transducer during progressive trypsin digestion for 1 hour.The result showed that ultrasound speed increased and ultrasound amplitude attenuation decreased in articular cartilage with PG digestion.However, Broadband ultrasound attenuation was non-sensitive to PG degeneration.The results maybe provide some information for diagnosing of early AC diseases.
ultrasound articular cartilage trypsin degeneration speed attenuation
SUN Feng WU Zhiyong SHAO Xiaoning WANG Yuexiang ZHANG Lihai NIU Haijun
School of Biological Science and Medical Engineering,Beihang University,Beijing,China Department of Ultrasound,People Liberation Army General Hospital,Beijing,China
国际会议
北京
英文
1-3
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）