NONINVASIVE ESTIMATION of PULMONARY VASCULAR RESISTANCE by COLOR M-MODE ECHOCARDIOGRAPHY ASSISTED with COMPUTER
Background The estimation of pulmonary vascular resistance (PVR) is of important in the diagnosis, management, and prognosis of cardiac disease; however, Doppler estimation of PVR is still considered unreliable and clumsy. The goal of this study was to seek a new method for noninvasive estimation of PVR by velocity propagation (VP) within the main pulmonary artery from color M-mode Doppler imaging using custom software on a personal computer. Methods: Color M-mode imaging of the pulmonary flow was obtained and then transferred onto a computer. The flow wave front of the first aliasing velocity was identified with the custom software, then regressed to a straight line. The slope representing VP of the pulmonary flow was automatically obtained. Comparative studies between this color M-mode Doppler echocardiography and cardiac catheterization for predicting PVR were performed in 20 children with congenital heart disease and 20 normal children. Results: VP of children with congenital heart disease were significant lower than those of normal children obtained by color M-mode Doppler echocardiography (38.38 ± 18.89 vs 80.34 ± 15.65; P<0.01) and correlated well with invasive PVR measurements (r=-0.69; P<0.01). The correlation and repeatability of the VP obtained by the custom software werebetter than the VP obtained by Doppler echocardiography (r=-0.78; P<0.01). A VP cutoff value obtained by the custom software of 35.910 had a sensitivity of 92.9％ and a specificity of 100％ to determine PVR>16 kPa.s/L. Conclusions: PVR could be accurately estimated by VP within the pulmonary artery obtained by color M-mode echocardiography using custom software on a personal computer.
pulmonary vascular resistance echocardiography congenital heart disease
Yuqi Zhanga Kun Sun Baoying Ye Guozhen Chen Lanping Wu Zhifang Zhang
Department of Pediatric Cardiology,Shanghai Childrens Medical Center,Shanghai Jiaotong University,S Department of Ultrasound,International Peace Maternity & Child Health Hospital of China Welfare Inst
国际会议
北京
英文
1-5
2009-06-11（万方平台首次上网日期，不代表论文的发表时间）