Automated Synthesis of 18F-Fluoroacetate Using Ezplora FDG4 Module

摘要：

As radio-labeled acetate is a good candidate to detect glial metabolism in brains and prostate cancer, ethyl and sodium 18Ffluoroacetates were utilized in clinical PET check. A simple and fast method for preparation of ethyl and sodium 18Ffluoroacetates using Explora FDG4 module has been established. By this development, it has become possible to obtain ethyl and sodium 18Ffluoroacetate in a short synthesis time of 39 and 43 min and with a reproducible radiochemical yield of 49.6 ± 4.7％ and 43.1 ± 5.2％, (decay corrected). The radiochemical purity of ethyl and sodium 18Ffluoroacetates were more than 95％.

关键词： 18Ffluoroacetates automated synthesis PET tracer Ezplora FDG4 Module

作者: Li-Quan Sun Ai-Qin Luo Yasuhisa Fujibayashi

作者单位: School of Life Science and Technology Beijing Institute of Technology Beijing,100081,P.R.China Biomedical Imaging Research Center University of Fukui Fukui,910-1193,Japan

会议类型: 国际会议

会议名称: The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

会议地点: 北京

会议语种:英文

页码: 1-4

在线出版日期: 2009-06-11（万方平台首次上网日期，不代表论文的发表时间）