会议专题

Estimation of Concerted Activities Based on Subsequence Distribution Discrepancy Calculation

In the present study, a new measurement of subsequence distribution discrepancy (MSDD) was applied to analyze the concerted activity pattern of a group of spike trains. The changes of concerted pattern in a neuronal population affected by the activity of GABA inhibitory pathway were estimated using this method. Comparison between MSDD and classical cross-correlation analysis showed that the parameter Bk in MSDD can be considered as an index showing the degree of coincidence between the activity of the k-th neuron and that of the rest neurons in the group. These results suggest that the new algorithm MSDD can be applied to investigate the concerted activities of neuronal population efficiently. With the help of this method, physiological conditions determined by the spatiotemporal pattern of the neuronal activities can be compared.

multi-unit recording population activity multiple spike train analysis GABA inhibition

Xue Liu Hao Li Pei-Ji Liang

School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai,China

国际会议

The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)

北京

英文

1-3

2009-06-11(万方平台首次上网日期,不代表论文的发表时间)