A GENOME ASSEMBLY PLATFORM FOR NEXT-GENERATION SEQUENCING TECHNOLOGY

摘要：

With the development of the new genomic sequencing technologies, a lot of new assembly algorithms have emerged. This paper summarizes the basic principles of the new assembly algorithms widely recognized internationally and describes a genome assembly platform we developed. The platform integrates 4 main programs designed especially for users to facilitate operation. We compared the performance of the programs mentioned above with assembly results of sequenced reads of Helicobacter acinonychis genome and verified that Velvet is the best assembly algorithm at present according to both cost time and the length of N50.

关键词： Genome sequencing de novo assembly short read

作者: Lu Wenwen Lu Zhiyuan Wang Yaxu Sun Xiao

作者单位: State Key Laboratory of Bioelectronics,Southeast University,Nanjing 210096,China

会议类型: 国际会议

会议名称: The 6th International Forum on Post-genome Technologies(6IFPT)(第六届国际后基因组生命科学技术学术论坛)

会议地点: 北京

会议语种:英文

页码: 166-167

在线出版日期: 2009-09-17（万方平台首次上网日期，不代表论文的发表时间）