Diagnostic value of whole-body MRI with diffusion-weighted sequence for detection of peritoneal carcinomatosis in colorectal malignancy
Objective Purpose of our study was to assess the diagnostic accuracy of whole-body MRI with diffusion-weightedsequence(WB-DWI)to determine the peritoneal cancer index(PCI)in correlation with surgical and histopathological findings.Materials and methods 12 of 15 patients underwent preoperativeWB-MRI Followed by cytoreductive surgery for primary tumorsof the appendix(n = 4),colorectum(n = 8)and their peritoneal disease.A total of 156 regions were retrospectively reviewed by two experienced radiologists without the clinical information.The sensitivity,specificity,accuracy were calculated at 13 anatomic sites.The WB-DWIPCIand PCI type were compared with surgical and histopathological findings.Results The paired t test resulted in nostatistical difference between the WB-DWI PCI and surgicalPCI(P = 0.115).WB-DWIcorrectly predicted the PCI type in 11 of 12 patients with a high accuracy of 91.7%,including 6 of 6 patientswith small-volume tumor,4 of 5 patients with moderatevolume tumor,and 1 of 1patients with large-volume tumor.WB-DWIcorrectly depicted tumors in 65 of 79 regions with 14 false-negative regions and 18 false-positive regions.The overall sensitivity,specificity,and accuracy of WB-DWIfor the detection of peritonealtumors were,respectively,82.3%,74.7%and 79.5%.For lesions < 0.5 cm in diameter,WB-DWI shows a good sensitivity of 69.0%.Conclusions WB-DWI is a valuable workup tool to evaluate the PCI before cytoreductive surgery in patients with colorectal peritoneal maligancy.
Guoxiang Cai Huan Zhang Weixing Dai Caixia Fu Xu Yan Alto Stemmer Tong Tong
Department of Colorectal Surgery,Fudan University Shanghai Cancer Center,Shanghai 200032,China Department of Radiology,Fudan University Shanghai Cancer Center;Department of Oncology,Shanghai Medi Siemens Shenzhen Magnetic Resonance Ltd.Shenzhen,China MR Collaboration NE Asia,Siemens Healthcare,Shanghai,China MR Applications Development,Siemens Healthcare,Erlangen,Germany
国内会议
北京
英文
1-11
2017-05-19（万方平台首次上网日期，不代表论文的发表时间）