Gene Expression Profile after Activation of RIG-I in 5”ppp-dsRNA Challenged DF-1
1.Introduction RIG-I like receptors(RLRs) are pattern-recognition receptors(PRRs) and are cytosolic RNAhelicases.RLR can recognize non-self RNA via the binding of its RNA ligand to the pathogenassociated molecular pattern(PAMP) on viral RNA.It is known that RIG-I is absent in thechicken genome,but is present in the genome of ducks.Shao et al.found that duck RIG-I canelicit antiviral responses to avian influenza virus and infectious bursa disease virus,and that theantiviral activity of RIG-I varies across species(such as duck,goose,human and mouse).
Yang Chen Qi Xu Yang Li Ran Liu Zhengyang Huang Bin Wang Guohong Chen
The Key Laboratory of Animal Genetics and Breeding and Molecular Design of Jiangsu Province,Yangzhou University,Yangzhou 225009,P.R.China
国内会议
重庆
英文
715-717
2016-05-25(万方平台首次上网日期,不代表论文的发表时间)