Therapeutic effects of endoscopic therapy combined with enteral nutrition on acute severe biliary pancreatitis
Background Acute severe biliary pancreatitis (ASBP) is a severe and fatal disease, and the expenditure is huge and therapeutic effects are still not satisfactory.This study aimed to improve the therapeutic effects and reduce the expenditure of ASBP treatment.Methods One hundred and five patients diagnosed with ASBP were referred to our department from January 2004 to July 2009, Diagnosis was based on the 2007 criteria of the Chinese Society of Surgery.Patients were divided into two groups;the E group: 50 patients who underwent endoscopic retrograde choledochopancreatography (ERCP) + endoscopic sphincterotomy (EST) + endoscopic lithotripsy basket (ESR) +endoscopic retrograde biliary drainage (ERBD) and enteral nutrition (EN), and the R group: 55 patients who underwent traditional treatment without ERCP.Subsequently, subjective symptoms, signs, biochemical analysis, serum endotoxin, tumor necrosis factor α, grades by computed tomography (CT), cost of hospitalization and length of stay were compared between the two groups.Results All enrolled patients complied well with all therapeutic regimens.Endoscopic therapy that combined EN could significantly improve symptoms, clinical signs, laboratory values, tumor necrosis factor α and endotoxin while significantly reducing hospital expenditure and length of hospital stay.The experimental findings revealed that there were obvious advantages in the E group compared with the Rgroup.Conclusions Endoscopic therapy combined with EN is an effective, safe and economic therapeutic regimen of ASBP.
endoscopy enteral nutrition acute severe biliary pancreatitis therapeutic regimen
ZHOU Wen-ca LI Yu-min ZHANG Hui LI Xun ZHANG Lei MENG Wen-bo ZHU Ke-xiang ZHANG Quan-bao HE Min-yan
Department Ⅱ of General Surgery, the First Hospital of Lanzhou University, the First Clinical Medica The second Hospital of Lanzhou University, Key Laboratory of Digestive System Tumor, Gansu Province
国内会议
2015第八届全国ERCP学术研讨会暨第十一届中国西部国际治疗内镜高峰论坛
兰州
英文
346-349
2015-07-31（万方平台首次上网日期，不代表论文的发表时间）