Molecular epidemiological features of Mycobacterium tuberculosis in an endemic region of Henan Province,China
Henan Province is one of the regions with the highest tuberculosis (TB) burden in China.Among isolates collected from Zhongmou County,Henan,21.28% (10/47) of those from 2001 and 22.95% (10/61) from 2007 were resistant to at least one drug (isoniazid,rifampicin,ethambutol or streptomycin); 90.74% (98/108) of the isolates were from the Beijing family,and 108 exhibited 105 different mycobacterial interspersed repetitive unitsvariable number of tandem repeats patterns.This study preliminarily reveals that Henan Province is still a high prevalence region for drug-resistant TB,and strains collected from local TB cases have diverse genotypes,of which the Beijing family type is predominant.
Mycobacterium tuberculosis prevalence drug resistance Beijing family MIRU-VNTR
H.Li H.Y.Yang X.G.Ma S.W.Ma Y.Zhang
Henan Center for Disease Control and Prevention,Zhengzhou,China W Harry Feinstone Department of Molecular Microbiology and Immunology,Bloomberg School of Public Hea
国内会议
武夷山
英文
47-50
2012-12-22（万方平台首次上网日期，不代表论文的发表时间）