Infusion of Hyperoxygenated Solution on Acute Haemorrhagic Shock in Rabbits
Tissue anoxia is the main mechanism of the shock reaction.Here,the effect of hyperoxygenated solution (HOS) on acute haemorrhagic shock was studied in rabbits.At 60 min after shock,rabbits were infused intravenously with hyperoxygenated solution at 10 (HOS1 group) or 20 ml/kg (HOS2 group) or with Ringer” s solution at 10 ml/kg (RS group).Compared with values before shock,values after shock were lower for mean arterial pressure (MAP),more negative for base excess (BE) and higher for blood lactate (BL) and blood viscosity.After infusion,MAP declined more slowly in the HOS1 and HOS2 groups than in the RS group.At 30 and 60 min after infusion,arterial partial pressure of oxygen (PaO2) and oxygen saturation (SaO2) were higher and BE was less negative in the HOS1 and HOS2 groups than in the RS group,BL was lower in the HOS1 and HOS2 groups than in the RS group,and PaO2 and SaO2 were higher in the HOS2 group than in the HOS1 group (with the exception of PaO2 at 60 min).It was concluded that HOS infusion can rectify changes in vital signs more effectively than Ringer” s solution after acute haemorrhagic shock in rabbits.
韩丽春 徐浩 白晓鋆 徐礼鲜
陕西省肿瘤医院麻醉科 710061 第四军医大学口腔医院麻醉科 710032
国内会议
西安
英文
246-247
2012-07-06（万方平台首次上网日期，不代表论文的发表时间）