The Rhodiola L.:A review on its phytochemistry,anticancer activity and future perspectives
Ethnopharmacological relevance:The Rhodiola L.(Crassulaceae,景天科),is a genus consisting of about 133 species and an aromatic plant found in mountainous regions around the world,most of which distributed in QTP and adjacent areas.As a medicinal and edible food,Rhodiola L.is widely used not only for its adaptogenic activities,able to enhance physical and cognitive performance,to relief multiple stress symptoms,but also exerts a various pharmacologic properties including antidepressive,antiinflammatory,antidiabetic,antiviral,anticancer,hepatoprotective and antioxidant activities,especially many CMS-related diseases,such as for the treatment HAPCin Tibetan medicine.Aim of this review:This review aims to provide up-to-date information on the chemical constituents,anticancer activity,species of thie Rhodiola L.and available drugs.Ultimately,to uncover the existing problems and provide practical solutions.Materials and Methods:Relevant literatures on the Rhodiola L.was obtained by an online search of worldwide-accepted scientific databases(Google Scholar,Web of Science,Sciencedirect,Elsevier,Springer,ACS Publications,CNKI,and Wanfang database).We also keep a watchful eye on conference proceedings,journal reference lists and abstracts from international scientific meetings,immortal works in Tibetan medicine(China)and TCM from different dynasties,and a computer-aided multiple softwares were employed for statistical analysis and graphical illustration.Results:Phytochemical investigations have revealed that the major chemical constituents of the Rhodiola L.are polysaccharides,flavonoids,glycosides,organic acids,volatile compounds,steroids,triterpenes,alkaloids,and nucleosides.These compounds have been proven to be the main bioactive substances responsible for pharmacological activities.Conclusions:A variety of dosage forms of the Rhodiola L.are currently being applied to patients suffering from various diseases, including multiple cancer. Nevertheless, further research is needed to be investigated.
Tibetan medicine Rhodiola L. phytochemistry anticancer activity future perspectives
Xiaobo Wang Ya Hou Yao Hu Yangyang Yu Tong Xu Yan Tang Kui Zhou Jing Zhang Yi Zhang Xianli Meng
School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China;Institute Ethnic Medicine College,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China;Institute
国内会议
南宁
英文
84-106
2018-05-01（万方平台首次上网日期，不代表论文的发表时间）